Osteopontin—A Master Regulator of Epithelial-Mesenchymal Transition

Osteopontin (OPN) plays an important functional role in both physiologic and pathologic states. OPN is implicated in the progression of fibrosis, cancer, and metastatic disease in several organ systems. The epithelial-mesenchymal transition (EMT), first described in embryology, is increasingly being...

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Dettagli Bibliografici
Pubblicato in:J Clin Med
Autori principali: Kothari, Anai N., Arffa, Matthew L., Chang, Victor, Blackwell, Robert H., Syn, Wing-Kin, Zhang, Jiwang, Mi, Zhiyong, Kuo, Paul C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2016
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850462/
https://ncbi.nlm.nih.gov/pubmed/27023622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm5040039
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