Paracrine Factors from Irradiated Peripheral Blood Mononuclear Cells Improve Skin Regeneration and Angiogenesis in a Porcine Burn Model

Burn wounds pose a serious threat to patients and often require surgical treatment. Skin grafting aims to achieve wound closure but requires a well-vascularized wound bed. The secretome of peripheral blood mononuclear cells (PBMCs) has been shown to improve wound healing and angiogenesis. We hypothe...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Hacker, Stefan, Mittermayr, Rainer, Nickl, Stefanie, Haider, Thomas, Lebherz-Eichinger, Diana, Beer, Lucian, Mitterbauer, Andreas, Leiss, Harald, Zimmermann, Matthias, Schweiger, Thomas, Keibl, Claudia, Hofbauer, Helmut, Gabriel, Christian, Pavone-Gyöngyösi, Mariann, Redl, Heinz, Tschachler, Erwin, Mildner, Michael, Ankersmit, Hendrik Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850437/
https://ncbi.nlm.nih.gov/pubmed/27125302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25168
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