High dose ionizing radiation regulates micro RNA and gene expression changes in human peripheral blood mononuclear cells

BACKGROUND: High dose ionizing radiation (IR) induces potent toxic cell effects mediated by either direct DNA damage or the production of reactive oxygen species (ROS). IR-induced modulations in multiple biological processes have been proposed to be partly regulated by radiosensitive microRNA (miRNA...

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Autori principali: Beer, Lucian, Seemann, Rudolf, Ristl, Robin, Ellinger, Adolf, Kasiri, Mohammad Mahdi, Mitterbauer, Andreas, Zimmermann, Matthias, Gabriel, Christian, Gyöngyösi, Mariann, Klepetko, Walter, Mildner, Michael, Ankersmit, Hendrik Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182888/
https://ncbi.nlm.nih.gov/pubmed/25257395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-814
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