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Novel method for the high-throughput production of phosphorylation site-specific monoclonal antibodies

Threonine phosphorylation accounts for 10% of all phosphorylation sites compared with 0.05% for tyrosine and 90% for serine. Although monoclonal antibody generation for phospho-serine and -tyrosine proteins is progressing, there has been limited success regarding the production of monoclonal antibod...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kurosawa, Nobuyuki, Wakata, Yuka, Inobe, Tomonao, Kitamura, Haruki, Yoshioka, Megumi, Matsuzawa, Shun, Kishi, Yoshihiro, Isobe, Masaharu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850396/
https://ncbi.nlm.nih.gov/pubmed/27125496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25174
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