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Development and validation of monoclonal antibodies against N6-methyladenosine for the detection of RNA modifications

RNA contains various chemical modifications, among which N6-methyladenosine (m6A) is the most prevalent modified nucleotide in eukaryotic mRNA. Emerging evidence suggests that m6A plays an important role in regulating a variety of cellular functions by controlling mRNA processing, translation and de...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Matsuzawa, Shun, Wakata, Yuka, Ebi, Fumiya, Isobe, Masaharu, Kurosawa, Nobuyuki
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774519/
https://ncbi.nlm.nih.gov/pubmed/31577817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223197
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