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The Eng1 β-Glucanase Enhances Histoplasma Virulence by Reducing β-Glucan Exposure

The fungal pathogen Histoplasma capsulatum parasitizes host phagocytes. To avoid antimicrobial immune responses, Histoplasma yeasts must minimize their detection by host receptors while simultaneously interacting with the phagocyte. Pathogenic Histoplasma yeast cells, but not avirulent mycelial cell...

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Détails bibliographiques
Publié dans:mBio
Auteurs principaux: Garfoot, Andrew L., Shen, Qian, Wüthrich, Marcel, Klein, Bruce S., Rappleye, Chad A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850272/
https://ncbi.nlm.nih.gov/pubmed/27094334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01388-15
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