Function of the Borrelia burgdorferi FtsH Homolog Is Essential for Viability both In Vitro and In Vivo and Independent of HflK/C

In many bacteria, the FtsH protease and its modulators, HflK and HflC, form a large protein complex that contributes to both membrane protein quality control and regulation of the cellular response to environmental stress. Both activities are crucial to the Lyme disease pathogen Borrelia burgdorferi...

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Udgivet i:mBio
Main Authors: Chu, Chen-Yi, Stewart, Philip E., Bestor, Aaron, Hansen, Bryan, Lin, Tao, Gao, Lihui, Norris, Steven J., Rosa, Patricia A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850261/
https://ncbi.nlm.nih.gov/pubmed/27094329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00404-16
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