Function of the Borrelia burgdorferi FtsH Homolog Is Essential for Viability both In Vitro and In Vivo and Independent of HflK/C

In many bacteria, the FtsH protease and its modulators, HflK and HflC, form a large protein complex that contributes to both membrane protein quality control and regulation of the cellular response to environmental stress. Both activities are crucial to the Lyme disease pathogen Borrelia burgdorferi...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Chu, Chen-Yi, Stewart, Philip E., Bestor, Aaron, Hansen, Bryan, Lin, Tao, Gao, Lihui, Norris, Steven J., Rosa, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850261/
https://ncbi.nlm.nih.gov/pubmed/27094329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00404-16
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