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SNX9 promotes metastasis by enhancing cancer cell invasion via differential regulation of RhoGTPases

Despite current advances in cancer research, metastasis remains the leading factor in cancer-related deaths. Here we identify sorting nexin 9 (SNX9) as a new regulator of breast cancer metastasis. We detect an increase in SNX9 expression in human breast cancer metastases compared with primary tumors...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Bendris, Nawal, Williams, Karla C., Reis, Carlos R., Welf, Erik S., Chen, Ping-Hung, Lemmers, Bénédicte, Hahne, Michael, Leong, Hon Sing, Schmid, Sandra L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850029/
https://ncbi.nlm.nih.gov/pubmed/26960793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-02-0101
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