Epitope Spreading of Autoantibody Response to PLA2R Associates with Poor Prognosis in Membranous Nephropathy

The phospholipase A2 receptor (PLA2R1) is the major autoantigen in idiopathic membranous nephropathy. However, the value of anti-PLA2R1 antibody titers in predicting patient outcomes is unknown. Here, we screened serum samples from 50 patients positive for PLA2R1 for immunoreactivity against a serie...

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Bibliografske podrobnosti
izdano v:J Am Soc Nephrol
Main Authors: Seitz-Polski, Barbara, Dolla, Guillaume, Payré, Christine, Girard, Christophe A., Polidori, Joel, Zorzi, Kevin, Birgy-Barelli, Eléonore, Jullien, Perrine, Courivaud, Cécile, Krummel, Thierry, Benzaken, Sylvia, Bernard, Ghislaine, Burtey, Stéphane, Mariat, Christophe, Esnault, Vincent L.M., Lambeau, Gérard
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2016
Teme:
Clinical Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849812/
https://ncbi.nlm.nih.gov/pubmed/26567246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014111061
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