Anti-PLA2R1 Antibodies Containing Sera Induce In Vitro Cytotoxicity Mediated by Complement Activation

The phospholipase A2 receptor (PLA2R1) is the major autoantigen in idiopathic membranous nephropathy (MN). However, the pathogenic role of anti-PLA2R1 autoantibodies is unclear. Our aim was to evaluate the in vitro cytotoxicity of anti-PLA2R1 antibodies mediated by complement. Forty-eight patients w...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Lateb, Maël, Ouahmi, Hajar, Payré, Christine, Brglez, Vesna, Zorzi, Kevin, Dolla, Guillaume, Zaidan, Mohamad, Boyer-Suavet, Sonia, Knebelmann, Bertrand, Crépin, Thomas, Courivaud, Cécile, Jourde-Chiche, Noémie, Esnault, Vincent, Lambeau, Gérard, Seitz-Polski, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012209/
https://ncbi.nlm.nih.gov/pubmed/32083137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1324804
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