ABHD5/CGI-58, the Chanarin-Dorfman Syndrome Protein, Mobilises Lipid Stores for Hepatitis C Virus Production

Hepatitis C virus (HCV) particles closely mimic human very-low-density lipoproteins (VLDL) to evade humoral immunity and to facilitate cell entry. However, the principles that govern HCV association with VLDL components are poorly defined. Using an siRNA screen, we identified ABHD5 (α/β hydrolase do...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Vieyres, Gabrielle, Welsch, Kathrin, Gerold, Gisa, Gentzsch, Juliane, Kahl, Sina, Vondran, Florian W. R., Kaderali, Lars, Pietschmann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849665/
https://ncbi.nlm.nih.gov/pubmed/27124600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005568
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