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Disruption of the Arabidopsis CGI-58 homologue produces Chanarin–Dorfman-like lipid droplet accumulation in plants

CGI-58 is the defective gene in the human neutral lipid storage disease called Chanarin-Dorfman syndrome. This disorder causes intracellular lipid droplets to accumulate in nonadipose tissues, such as skin and blood cells. Here, disruption of the homologous CGI-58 gene in Arabidopsis thaliana result...

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Detalhes bibliográficos
Main Authors: James, Christopher N., Horn, Patrick J., Case, Charlene R., Gidda, Satinder K., Zhang, Daiyuan, Mullen, Robert T., Dyer, John M., Anderson, Richard G. W., Chapman, Kent D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955100/
https://ncbi.nlm.nih.gov/pubmed/20876112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911359107
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