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Transgenic Expression of Human Lysophosphatidic Acid Receptor LPA(2) in Mouse Intestinal Epithelial Cells Induces Intestinal Dysplasia
Lysophosphatidic acid (LPA) acts on LPA(2) receptor to mediate multiple pathological effects that are associated with tumorigenesis. The absence of LPA(2) attenuates tumor progression in rodent models of colorectal cancer, but whether overexpression of LPA(2) alone can lead to malignant transformati...
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| Publicado no: | PLoS One |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4849659/ https://ncbi.nlm.nih.gov/pubmed/27124742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154527 |
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