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The Chp1 chromodomain binds the H3K9me tail and the nucleosome core to assemble heterochromatin

To maintain genome stability, cells pack large portions of their genome into silent chromatin or heterochromatin. Histone H3 lysine 9 methylation, a hallmark of heterochromatin, is recognized by conserved readers called chromodomains. But how chromodomains interact with their actual binding partner,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Discov
Prif Awduron: Zocco, Manuel, Marasovic, Mirela, Pisacane, Paola, Bilokapic, Silvija, Halic, Mario
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849473/
https://ncbi.nlm.nih.gov/pubmed/27462451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.4
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