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Postsynaptic density levels of the NMDA receptor NR1 subunit and PSD-95 protein in prefrontal cortex from people with schizophrenia

BACKGROUND: There is converging evidence of involvement of N-methyl-d-aspartate (NMDA) receptor hypofunction in the pathophysiology of schizophrenia. Our group recently identified a decrease in total NR1 mRNA and protein expression in the dorsolateral prefrontal cortex in a case-control study of ind...

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Detalhes bibliográficos
Publicado no:NPJ Schizophr
Main Authors: Catts, Vibeke Sørensen, Derminio, Dominique Suzanne, Hahn, Chang-Gyu, Weickert, Cynthia Shannon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849460/
https://ncbi.nlm.nih.gov/pubmed/27336043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjschz.2015.37
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