Affinity purification-mass spectrometry analysis of bcl-2 interactome identified SLIRP as a novel interacting protein

Members of the bcl-2 protein family share regions of sequence similarity, the bcl-2 homology (BH) domains. Bcl-2, the most studied member of this family, has four BH domains, BH1–4, and has a critical role in resistance to antineoplastic drugs by regulating the mitochondrial apoptotic pathway. Moreo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Trisciuoglio, D, Desideri, M, Farini, V, De Luca, T, Di Martile, M, Tupone, M G, Urbani, A, D'Aguanno, S, Del Bufalo, D
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849145/
https://ncbi.nlm.nih.gov/pubmed/26866271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.357
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