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Distinguishing Hypertrophic Cardiomyopathy-Associated Mutations from Background Genetic Noise

Despite the significant progress that has been made in identifying disease-associated mutations, the utility of the Hypertrophic Cardiomyopathy (HCM) genetic test is limited by a lack of understanding of the background genetic variation inherent to these sarcomeric genes in seemingly healthy subject...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Transl Res
Main Authors: Kapplinger, Jamie D., Landstrom, Andrew P., Bos, J. Martijn, Salisbury, Benjamin A., Callis, Thomas E., Ackerman, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849132/
https://ncbi.nlm.nih.gov/pubmed/24510615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-014-9542-z
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