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Water Mediates Recognition of DNA Sequence via Ionic Current Blockade in a Biological Nanopore

Electric field-driven translocation of DNA strands through biological nanopores has been shown to produce blockades of the nanopore ionic current that depend on the nucleotide composition of the strands. Coupling a biological nanopore MspA to a DNA processing enzyme has made DNA sequencing via measu...

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Bibliographic Details
Published in:ACS Nano
Main Authors: Bhattacharya, Swati, Yoo, Jejoong, Aksimentiev, Aleksei
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849127/
https://ncbi.nlm.nih.gov/pubmed/27054820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.6b00940
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