Selected novel 5'-amino-2'-hydroxy-1, 3-diaryl-2-propen-1-ones arrest cell cycle of HCT-116 in G(0)/G(1 ) phase

A series of 5'-amino-2'-hydroxy-1,3-diaryl-2-propen-1-ones (AC1-AC15) were synthesized by Claisen-Schmidt condensation of 5'-acetamido-2'-hydroxy acetophenone with various substituted aromatic aldehydes. The synthesized compounds were characterized by FTIR, (1)H NMR and mass spec...

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Publicado en:EXCLI J
Autores principales: Simon, Lalitha, Srinivasan, K. K., Kumar, Nitesh, Reddy, Neetinkumar D., Biswas, Subhankar, Rao, C. Mallikarjuna, Moorkoth, Sudheer
Formato: Artigo
Lenguaje:Inglês
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849104/
https://ncbi.nlm.nih.gov/pubmed/27152112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2015-610
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