Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death and its prognosis remains poor due to the high risk of tumor recurrence and metastasis. Berberine (BBR) is a natural compound derived from some medicinal plants, and accumulating evidence has shown its potent anti-tum...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wang, Xuanbin, Wang, Ning, Li, Hongliang, Liu, Ming, Cao, Fengjun, Yu, Xianjun, Zhang, Jingxuan, Tan, Yan, Xiang, Longchao, Feng, Yibin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849033/
https://ncbi.nlm.nih.gov/pubmed/27092498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17040577
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