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uPA Binding to PAI-1 Induces Corneal Myofibroblast Differentiation on Vitronectin
PURPOSE. Vitronectin (VN) in provisional extracellular matrix (ECM) promotes cell migration. Fibrotic ECM also includes VN and, paradoxically, strongly adherent myofibroblasts (Mfs). Because fibrotic Mfs secrete elevated amounts of urokinase plasminogen activator (uPA), we tested whether increased e...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949353/ https://ncbi.nlm.nih.gov/pubmed/22700714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10042 |
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