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uPA Binding to PAI-1 Induces Corneal Myofibroblast Differentiation on Vitronectin

PURPOSE. Vitronectin (VN) in provisional extracellular matrix (ECM) promotes cell migration. Fibrotic ECM also includes VN and, paradoxically, strongly adherent myofibroblasts (Mfs). Because fibrotic Mfs secrete elevated amounts of urokinase plasminogen activator (uPA), we tested whether increased e...

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書誌詳細
主要な著者: Wang, Lingyan, Ly, Christine M., Ko, Chun-Ying, Meyers, Erin E., Lawrence, Daniel A., Bernstein, Audrey M.
フォーマット: Artigo
言語:Inglês
出版事項: The Association for Research in Vision and Ophthalmology 2012
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949353/
https://ncbi.nlm.nih.gov/pubmed/22700714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10042
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