Structural Investigation for Optimization of Anthranilic Acid Derivatives as Partial FXR Agonists by in Silico Approaches

In this paper, a three level in silico approach was applied to investigate some important structural and physicochemical aspects of a series of anthranilic acid derivatives (AAD) newly identified as potent partial farnesoid X receptor (FXR) agonists. Initially, both two and three-dimensional quantit...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Chen, Meimei, Yang, Xuemei, Lai, Xinmei, Kang, Jie, Gan, Huijuan, Gao, Yuxing
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848992/
https://ncbi.nlm.nih.gov/pubmed/27070594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17040536
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