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Identfication of Potent LXRβ-Selective Agonists without LXRα Activation by In Silico Approaches
Activating Liver X receptors (LXRs) represents a promising therapeutic option for dyslipidemia. However, activating LXRα may cause undesired lipogenic effects. Discovery of highly LXRβ-selective agonists without LXRα activation were indispensable for dyslipidemia. In this study, in silico approaches...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6099648/ https://ncbi.nlm.nih.gov/pubmed/29867043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23061349 |
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