Intranasal Immunization with Influenza Virus-Like Particles Containing Membrane-Anchored Cholera Toxin B or Ricin Toxin B Enhances Adaptive Immune Responses and Protection against an Antigenically Distinct Virus

Vaccination is the most effective means to prevent influenza virus infection, although current approaches are associated with suboptimal efficacy. Here, we generated virus-like particles (VLPs) composed of the hemagglutinin (HA), neuraminidase (NA) and matrix protein (M1) of A/Changchun/01/2009 (H1N...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Ji, Xianliang, Ren, Zhiguang, Xu, Na, Meng, Lingnan, Yu, Zhijun, Feng, Na, Sang, Xiaoyu, Li, Shengnan, Li, Yuanguo, Wang, Tiecheng, Zhao, Yongkun, Wang, Hualei, Zheng, Xuexing, Jin, Hongli, Li, Nan, Yang, Songtao, Cao, Jinshan, Liu, Wensen, Gao, Yuwei, Xia, Xianzhu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848608/
https://ncbi.nlm.nih.gov/pubmed/27110810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8040115
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