Intranasal Immunization with Influenza Virus-Like Particles Containing Membrane-Anchored Cholera Toxin B or Ricin Toxin B Enhances Adaptive Immune Responses and Protection against an Antigenically Distinct Virus

Vaccination is the most effective means to prevent influenza virus infection, although current approaches are associated with suboptimal efficacy. Here, we generated virus-like particles (VLPs) composed of the hemagglutinin (HA), neuraminidase (NA) and matrix protein (M1) of A/Changchun/01/2009 (H1N...

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Publicado en:Viruses
Main Authors: Ji, Xianliang, Ren, Zhiguang, Xu, Na, Meng, Lingnan, Yu, Zhijun, Feng, Na, Sang, Xiaoyu, Li, Shengnan, Li, Yuanguo, Wang, Tiecheng, Zhao, Yongkun, Wang, Hualei, Zheng, Xuexing, Jin, Hongli, Li, Nan, Yang, Songtao, Cao, Jinshan, Liu, Wensen, Gao, Yuwei, Xia, Xianzhu
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848608/
https://ncbi.nlm.nih.gov/pubmed/27110810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8040115
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