Marburg virus-like particles by co-expression of glycoprotein and matrix protein in insect cells induces immune responses in mice

Abstract Background Marburg virus (MARV) causes severe haemorrhagic fever in humans and nonhuman primates and has a high mortality rate. However, effective drugs or licensed vaccines are not currently available to control the outbreak and spread of this disease. Methods In this study, we generated M...

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Detalhes bibliográficos
Main Authors: Weiwei Gai, Xuexing Zheng, Chong Wang, Hualei Wang, Yongkun Zhao, Qi Wang, Gary Wong, Weijiao Zhang, Na Feng, Boning Qiu, Hang Chi, Nan Li, Tiecheng Wang, Yuwei Gao, Junjie Shan, Songtao Yang, Xianzhu Xia
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-10-01
Colecção:Virology Journal
Assuntos:
Marburg virus
Virus-like particle
Adjuvant
Vaccine
Immune response
Acesso em linha:http://link.springer.com/article/10.1186/s12985-017-0869-3
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