Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer

Although early detection and treatment of prostate cancer (PCa) improves outcomes, many patients still die of metastatic PCa. Here, we report that metastatic PCa exhibits reduced levels of the microRNAsmiR-101 and miR-27a. These micro-RNAs (miRNAs) negatively regulate cell invasion and inhibit the e...

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Publicado no:Nat Commun
Main Authors: Lin, Shih-Chieh, Kao, Chung-Yang, Lee, Hui-Ju, Creighton, Chad J., Ittmann, Michael M., Tsai, Shaw-Jenq, Tsai, Sophia Y., Tsai, Ming-Jer
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848536/
https://ncbi.nlm.nih.gov/pubmed/27108958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11418
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