COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis

Mutations in phosphatase and tensin homologue (PTEN) or genomic alterations in the phosphatidylinositol-3-OH kinase-signalling pathway are the most common genetic alterations reported in human prostate cancer(1–4). However, the precise mechanism underlying how indolent tumours with PTEN alterations...

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Detalhes bibliográficos
Main Authors: Qin, Jun, Wu, San-Pin, Creighton, Chad J., Dai, Fangyan, Xie, Xin, Cheng, Chiang-Min, Frolov, Anna, Ayala, Gustavo, Lin, Xia, Feng, Xin-Hua, Ittmann, Michael M., Tsai, Shaw-Jenq, Tsai, Ming-Jer, Tsai, Sophia Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022346/
https://ncbi.nlm.nih.gov/pubmed/23201680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11674
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