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The early history and emergence of molecular functions and modular scale-free network behavior

The formation of protein structural domains requires that biochemical functions, defined by conserved amino acid sequence motifs, be embedded into a structural scaffold. Here we trace domain history onto a bipartite network of elementary functional loop sequences and domain structures defined at the...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Aziz, M. Fayez, Caetano-Anollés, Kelsey, Caetano-Anollés, Gustavo
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848518/
https://ncbi.nlm.nih.gov/pubmed/27121452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25058
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