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The early history and emergence of molecular functions and modular scale-free network behavior

The formation of protein structural domains requires that biochemical functions, defined by conserved amino acid sequence motifs, be embedded into a structural scaffold. Here we trace domain history onto a bipartite network of elementary functional loop sequences and domain structures defined at the...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Aziz, M. Fayez, Caetano-Anollés, Kelsey, Caetano-Anollés, Gustavo
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848518/
https://ncbi.nlm.nih.gov/pubmed/27121452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25058
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