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High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer’s disease

Abnormal accumulation of brain metals is a key feature of Alzheimer’s disease (AD). Formation of amyloid-β plaque cores (APC) is related to interactions with biometals, especially Fe, Cu and Zn, but their particular structural associations and roles remain unclear. Using an integrative set of advanc...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Plascencia-Villa, Germán, Ponce, Arturo, Collingwood, Joanna F., Arellano-Jiménez, M. Josefina, Zhu, Xiongwei, Rogers, Jack T., Betancourt, Israel, José-Yacamán, Miguel, Perry, George
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848473/
https://ncbi.nlm.nih.gov/pubmed/27121137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24873
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