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Posttranslational Modifications and the Immunogenicity of Biotherapeutics
Whilst the amino acid sequence of a protein is determined by its gene sequence, the final structure and function are determined by posttranslational modifications (PTMs), including quality control (QC) in the endoplasmic reticulum (ER) and during passage through the Golgi apparatus. These processes...
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| Publicado no: | J Immunol Res |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4848426/ https://ncbi.nlm.nih.gov/pubmed/27191002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5358272 |
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