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Posttranslational Modifications and the Immunogenicity of Biotherapeutics
Whilst the amino acid sequence of a protein is determined by its gene sequence, the final structure and function are determined by posttranslational modifications (PTMs), including quality control (QC) in the endoplasmic reticulum (ER) and during passage through the Golgi apparatus. These processes...
Enregistré dans:
| Publié dans: | J Immunol Res |
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| Auteur principal: | |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Hindawi Publishing Corporation
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4848426/ https://ncbi.nlm.nih.gov/pubmed/27191002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5358272 |
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