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Morphine-induced antinociception and reward in “humanized” mice expressing the mu opioid receptor A118G polymorphism
The rewarding and antinociceptive effects of opioids are mediated through the mu-opioid receptor. The A118G single nucleotide polymorphism in this receptor has been implicated in drug addiction and differences in pain response. Clinical and preclinical studies have found that the G allele is associa...
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| Udgivet i: | Brain Res Bull |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4848164/ https://ncbi.nlm.nih.gov/pubmed/26521067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2015.10.007 |
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