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Sirtuins, cell senescence, and vascular aging

The sirtuin (SIRTs) constitute a class of proteins with NAD+-dependent deacetylase or ADP-ribosyltransferase activity. Seven SIRT family members have been identified in mammals, from SIRT1, the best studied for its role in vascular aging, to SIRT7. SIRT1 and SIRT2 are localized both in the nucleus a...

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Detalhes bibliográficos
Publicado no:Can J Cardiol
Main Authors: Kida, Yujiro, Goligorsky, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848124/
https://ncbi.nlm.nih.gov/pubmed/26948035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cjca.2015.11.022
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