A bacteriophage endolysin that eliminates intracellular streptococci

PlyC, a bacteriophage-encoded endolysin, lyses Streptococcus pyogenes (Spy) on contact. Here, we demonstrate that PlyC is a potent agent for controlling intracellular Spy that often underlies refractory infections. We show that the PlyC holoenzyme, mediated by its PlyCB subunit, crosses epithelial c...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Shen, Yang, Barros, Marilia, Vennemann, Tarek, Gallagher, D Travis, Yin, Yizhou, Linden, Sara B, Heselpoth, Ryan D, Spencer, Dennis J, Donovan, David M, Moult, John, Fischetti, Vincent A, Heinrich, Frank, Lösche, Mathias, Nelson, Daniel C
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2016
Fag:
Biochemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848087/
https://ncbi.nlm.nih.gov/pubmed/26978792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13152
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker