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Potential C-terminal-domain inhibitors of heat shock protein 90 derived from a C-terminal peptide helix
Hsp90 is a molecular chaperone implicated in many diseases including cancer and neurodegenerative disease. Most inhibitors target the ATPase site in Hsp90’s N-terminal domain, with relatively few inhibitors of other domains reported to date. Here, we show that peptides derived from a short helix at...
Gorde:
| Argitaratua izan da: | Bioorg Med Chem |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4847944/ https://ncbi.nlm.nih.gov/pubmed/24984936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.06.006 |
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