Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate

The T-box transcription factor TBX18 is essential to mesenchymal cell differentiation in several tissues and Tbx18 loss-of-function results in dramatic organ malformations and perinatal lethality. Here we demonstrate for the first time that Tbx18 is required for the normal development of periductal...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bolt, C. Chase, Negi, Soumya, Guimarães-Camboa, Nuno, Zhang, Huimin, Troy, Joseph M., Lu, Xiaochen, Kispert, Andreas, Evans, Sylvia M., Stubbs, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847854/
https://ncbi.nlm.nih.gov/pubmed/27120339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154413
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