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A distant downstream enhancer directs essential expression of Tbx18 in urogenital tissues

The vertebrate T-box transcription factor gene Tbx18 performs a vital role in development of multiple organ systems. Tbx18 insufficiency manifests as recessive phenotypes in the upper urinary system, cardiac venous pole, inner ear, and axial skeleton; homozygous null mutant animals die perinatally....

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Detalhes bibliográficos
Main Authors: Bolt, C. Chase, Elso, Colleen M., Lu, Xiaochen, Pan, Fuming, Kispert, Andreas, Stubbs, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104242/
https://ncbi.nlm.nih.gov/pubmed/24854998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.05.010
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