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A distant downstream enhancer directs essential expression of Tbx18 in urogenital tissues
The vertebrate T-box transcription factor gene Tbx18 performs a vital role in development of multiple organ systems. Tbx18 insufficiency manifests as recessive phenotypes in the upper urinary system, cardiac venous pole, inner ear, and axial skeleton; homozygous null mutant animals die perinatally....
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104242/ https://ncbi.nlm.nih.gov/pubmed/24854998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.05.010 |
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