GIFT4 fusokine converts leukemic B cells into immune helper cells

BACKGROUND: Chronic lymphocytic leukemia (CLL) remains incurable with standard therapy, and is characterized by excessive expansion of monoclonal abnormal mature B cells and more regulatory immune properties of T cell compartment. Thus, developing novel strategies to enhance immune function merits f...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Deng, Jiusheng, Pennati, Andrea, Cohen, Jonathon B., Wu, Yuanqiang, Ng, Spencer, Wu, Jian Hui, Flowers, Christopher R., Galipeau, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847253/
https://ncbi.nlm.nih.gov/pubmed/27118475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0865-1
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