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C1, a highly potent novel curcumin derivative, binds to tubulin, disrupts microtubule network and induces apoptosis
We have synthesized a curcumin derivative, 4-{5-(4-hydroxy-3-methoxy-phenyl)-2-[3-(4-hydroxy-3-methoxy-phenyl)-acryloyl]-3-oxo-penta-1,4-dienyl}-piperidine-1-carboxylic acid tert-butyl ester (C1) that displays much stronger antiproliferative activity against various types of cancer cells including m...
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| Veröffentlicht in: | Biosci Rep |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4847174/ https://ncbi.nlm.nih.gov/pubmed/26980197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160039 |
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