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Oxidative damage of copper chloride overload to the cultured rat astrocytes

Disorders of copper metabolism are associated with neurological dysfunction including Wilson’s disease (WD). WD is a autosomal recessive disorder caused by mutations in the ATP7B gene resulting in the inability of the hepatocytes to remove excess copper. Gradual copper accumulation causes damage to...

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Publicat a:Am J Transl Res
Autors principals: Hu, Hao-Lu, Ni, Xiu-Shi, Duff-Canning, Sarah, Wang, Xiao-Ping
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846971/
https://ncbi.nlm.nih.gov/pubmed/27158414
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