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Comparison between micro- and nanosized copper oxide and water soluble copper chloride: interrelationship between intracellular copper concentrations, oxidative stress and DNA damage response in human lung cells

BACKGROUND: Nano- and microscale copper oxide particles (CuO NP, CuO MP) are applied for manifold purposes, enhancing exposure and thus the potential risk of adverse health effects. Based on the pronounced in vitro cytotoxicity of CuO NP, systematic investigations on the mode of action are required....

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Publicado en:Part Fibre Toxicol
Main Authors: Strauch, Bettina Maria, Niemand, Rebecca Katharina, Winkelbeiner, Nicola Lisa, Hartwig, Andrea
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540434/
https://ncbi.nlm.nih.gov/pubmed/28764715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-017-0209-1
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