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Differential utilization of binding loop flexibility in T cell receptor ligand selection and cross-reactivity
Complementarity determining region (CDR) loop flexibility has been suggested to play an important role in the selection and binding of ligands by T cell receptors (TCRs) of the cellular immune system. However, questions remain regarding the role of loop motion in TCR binding, and crystallographic st...
Guardat en:
| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4846865/ https://ncbi.nlm.nih.gov/pubmed/27118724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25070 |
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