Angiogenesis genotyping and clinical outcome during regorafenib treatment in metastatic colorectal cancer patients

Regorafenib monotherapy is a potential option for metastatic colorectal cancer patients. However, the lack of predictive factors and the severe toxicities related to treatment have made its use in clinical practice challenging. Polymorphisms of VEGF and its receptor (VEGFR) genes might regulate angi...

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Publicado no:Sci Rep
Main Authors: Giampieri, Riccardo, Salvatore, Lisa, Del Prete, Michela, Prochilo, Tiziana, D’Anzeo, Marco, Loretelli, Cristian, Loupakis, Fotios, Aprile, Giuseppe, Maccaroni, Elena, Andrikou, Kalliopi, Bianconi, Maristella, Bittoni, Alessandro, Faloppi, Luca, Demurtas, Laura, Montironi, Rodolfo, Scarpelli, Marina, Falcone, Alfredo, Zaniboni, Alberto, Scartozzi, Mario, Cascinu, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846860/
https://ncbi.nlm.nih.gov/pubmed/27117754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25195
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