Angiogenesis genotyping and clinical outcome during regorafenib treatment in metastatic colorectal cancer patients

Regorafenib monotherapy is a potential option for metastatic colorectal cancer patients. However, the lack of predictive factors and the severe toxicities related to treatment have made its use in clinical practice challenging. Polymorphisms of VEGF and its receptor (VEGFR) genes might regulate angi...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Giampieri, Riccardo, Salvatore, Lisa, Del Prete, Michela, Prochilo, Tiziana, D’Anzeo, Marco, Loretelli, Cristian, Loupakis, Fotios, Aprile, Giuseppe, Maccaroni, Elena, Andrikou, Kalliopi, Bianconi, Maristella, Bittoni, Alessandro, Faloppi, Luca, Demurtas, Laura, Montironi, Rodolfo, Scarpelli, Marina, Falcone, Alfredo, Zaniboni, Alberto, Scartozzi, Mario, Cascinu, Stefano
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846860/
https://ncbi.nlm.nih.gov/pubmed/27117754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25195
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