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Towards Vast Libraries of Scaffold-Diverse, Conformationally Constrained Oligomers

There is great interest in the development of probe molecules and drug leads that would bind tightly and selectively to protein surfaces that are difficult to target with traditional molecules, such as those involved in protein-protein interactions. The currently available evidence suggests that thi...

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Detalles Bibliográficos
Publicado en:Chem Commun (Camb)
Main Authors: Kodadek, Thomas, McEnaney, Patrick
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846527/
https://ncbi.nlm.nih.gov/pubmed/26996593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc00617e
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