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Mutations for Worse or Better: Low Fidelity DNA Synthesis by SOS DNA Polymerase V is a Tightly-Regulated Double-Edged Sword

1953, the year of Watson and Crick, bore witness to a less acclaimed, yet highly influential discovery. Jean Weigle demonstrated that upon infection of Escherichia coli, λ phage deactivated by UV radiation, and thus unable to form progeny, could be reactivated by irradiation of the bacterial host. E...

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Dettagli Bibliografici
Pubblicato in:Biochemistry
Autori principali: Jaszczur, Malgorzata, Bertram, Jeffrey G., Robinson, Andrew, van Oijen, Antoine M., Woodgate, Roger, Cox, Michael M., Goodman, Myron F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846499/
https://ncbi.nlm.nih.gov/pubmed/27043933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00117
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