DERIVING HUMAN ENS LINEAGES FOR CELL THERAPY AND DRUG DISCOVERY IN HIRSCHSPRUNG'S DISEASE

The enteric nervous system (ENS) is the largest component of the autonomic nervous system with neuron numbers surpassing those present in the spinal cord(1). The ENS has been called the “second brain”(1) given its autonomy, remarkable neurotransmitter diversity and complex cytoarchitecture. Defects...

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Publicado en:Nature
Autores principales: Fattahi, Faranak, Steinbeck, Julius A, Kriks, Sonja, Tchieu, Jason, Zimmer, Bastian, Kishinevsky, Sarah, Zeltner, Nadja, Mica, Yvonne, El-Nachef, Wael, Zhao, Huiyong, de Stanchina, Elisa, Gershon, Michael D., Grikscheit, Tracy C., Chen, Shuibing, Studer, Lorenz
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846424/
https://ncbi.nlm.nih.gov/pubmed/26863197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16951
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