Antibody-targeted interleukin 2 stimulates T-cell killing of autologous tumor cells.

A genetically engineered fusion protein consisting of a chimeric anti-ganglioside GD2 antibody (ch14.18) and interleukin 2 (IL2) was tested for its ability to enhance the killing of autologous GD2-expressing melanoma target cells by a tumor-infiltrating lymphocyte line (660 TIL). The fusion of IL2 t...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Gillies, S D, Reilly, E B, Lo, K M, Reisfeld, R A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1992
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC48464/
https://ncbi.nlm.nih.gov/pubmed/1741398
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